spoVB [2017-8-11 16:0:3]

MurJ family lipid II flippase, spore cortex peptidoglycan synthesis

locus: BSU27670

pI: 10.19

mw: 55.91 kDa

protein length: 518 aa

gene length: 1554 bp

function: spore cortex peptidoglycan synthesis

product: sporulation-specific MurJ family lipid II flippase

essential: no

synonyms: spoIIIF

Genomic Context

categories

• [category|SW 1|Cellular processes] → [category|SW 1.1|Cell envelope and cell division] → [category|SW 1.1.1|Cell wall synthesis] → [category|SW 1.1.1.1|Biosynthesis of peptidoglycan]
• [category|SW 2|Metabolism] → [category|SW 2.6|Additional metabolic pathways] → [category|SW 2.6.1|Biosynthesis of cell wall components] → [category|SW 2.6.1.1|Biosynthesis of peptidoglycan]
• [category|SW 4|Lifestyles] → [category|SW 4.2|Sporulation] → [category|SW 4.2.1|Sporulation proteins] → [category|SW 4.2.1.4|Sporulation proteins/ other]
• [category|SW 6|Groups of genes] → [category|SW 6.2|Membrane proteins]

Gene

Coordinates: 2,829,564 → 2,831,120

The protein

Protein family

• [SW|MOP exporter family]

Paralogous protein(s)

• [protein|D6B1837075ECBEE1FEAC704DDB6795336092897F|YabM], [protein|34A5CD28A3DBCB10B4E1C82E50143FA73B553919|YkvU], [protein|0AFFB4B715CCE6B1C53BBB7F890EFB3126CB466E|MurJ]

Expression and Regulation

Operons

• genes: [gene|9633C40190B7D0EA264270FD44567C61A012AD15|spoVB]-[gene|C52461A2FE856C94E0D0701FB7412368404FC83B|yrzE]
  description: [pubmed|22383849]

  sigma factors

  • [protein|3CB24D493B3282278B7DC61CE3C793DFA815F9E2|SigE]: sigma factor, [pubmed|1744050], in [regulon|3CB24D493B3282278B7DC61CE3C793DFA815F9E2|SigE regulon]

  regulatory mechanism

  • [protein|90DCE4F286D2C151D8BDBF0E024E6BBEC94E2397|SpoIIID]: repression, [pubmed|15383836], in [regulon|90DCE4F286D2C151D8BDBF0E024E6BBEC94E2397|SpoIIID regulon]

  regulation

  • expressed early during sporulation in the mother cell ([protein|3CB24D493B3282278B7DC61CE3C793DFA815F9E2|SigE], [SW|SpoIIID]) [Pubmed|1744050,15383836]

References

• 19648239,19666716,1744050,15383836,25918422